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CEFOTAXIME SODIUM - DrugFuture

Cefotaxime sodium EUROPEAN PHARMACOPOEIA 7.0 Injection:10μL of the test solution and reference solutions (b), (c) and (d). Identification of impurities: use the chromatogram supplied with cefotaxime for peak identification CRS and the chromatogram obtained with reference solution (d) to identify thepeaksduetoimpuritiesA,B,C,EandF.

Cefotaxime sodium European Pharmacopoeia (EP) Reference ...

Cefotaxime sodium European Pharmacopoeia (EP) Reference Standard Synonym: Cefotaxim sodium salt, Cefotaxime sodium salt CAS Number 64485-93-4. Empirical Formula (Hill Notation) C 16 H 16 N 5 NaO 7 S 2. Molecular Weight 477.45 . Beilstein/REAXYS Number 5711411 . MDL number MFCD00079073. PubChem Substance ID 329774812. NACRES NA.24

Cefotaxime (Professional Patient Advice) - Drugs.com

EP0799232A1 EP95942724A EP95942724A EP0799232A1 EP 0799232 A1 EP0799232 A1 EP 0799232A1 EP 95942724 A EP95942724 A EP 95942724A EP 95942724 A EP95942724 A EP 95942724A EP 0799232 A1 EP0799232 A1 EP 0799232A1 Authority EP European Patent Office Prior art keywords formula compound cefotaxime acetone sodium salt Prior art date 1994-12-23 Legal status …

Cefotaxime | C16H17N5O7S2 - PubChem

Cefotaxime is a cephalosporin compound having acetoxymethyl and [2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side groups. It has a role as a drug allergen and an antibacterial drug. It is a member of 1,3-thiazoles, an oxime O-ether and a cephalosporin. It is a conjugate acid of a cefotaxime…

cefotaxime acid, cefotaxime acid Suppliers and ...

847 cefotaxime acid products are offered for sale by suppliers on Alibaba.com A wide variety of cefotaxime acid options are available to you, such as food grade, medicine grade. You can also choose from pharmaceutical intermediates cefotaxime acid There are 48 suppliers who sells cefotaxime acid on Alibaba.com, mainly located in Asia.

Cefotaxime sodium: A new and efficient corrosion inhibitor ...

High inhibition efficiency of cefotaxime sodium is attributed to presence of free NH 2 group which gets strongly protonated in hydrochloric acid solution. Week protonation of pyridine N of cefatrexyl gives low inhibition efficiency. 4. Conclusion. The inhibition efficiency of cefotaxime sodium increases with increase in the inhibitor concentration.

PRODUCTS-Cefotaxime Sodium,Cefotaxime Acid,Ceftriaxone ...

Cefotaxime Sodium. NameCefotaxime Sodium/ Sterile cefotaxime sodium for injectionDescriptionCefotaxime sodium is the third generation of semi-synthetic cephalosporin, used for sensitive bacteria caused by respiratory tract, urinary tract, bone and joint, skin and soft tissue, abdominal cavity, bile duct, digestive tract, facial features, genitals and other parts of the infection, burns, trauma ...

DailyMed - CEFOTAXIME- cefotaxime injection powder, for ...

Aug 01, 2019· July 09, 2019. Temporary Importation of Cefotaxime for Injection to Address Drug Shortage . Dear Healthcare Professional: Due to the current critical shortage of Cefotaxime for Injection products in the United States (U.S.) market, SteriMax Inc. (SteriMax), in conjunction with Apollo Pharmaceuticals USA Inc. (Apollo) and FFF Enterprises (FFF), is coordinating with the U.S. Food and …

CEFODIZIME SODIUM PDF

Enoxaparin The therapeutic efficacy of Enoxaparin can be decreased when used in combination with Cefotaxime. Saxagliptin Cefotaxime may decrease the excretion rate of Saxagliptin which could result in a higher serum level. Magnesium chloride Cefotaxime may decrease the excretion rate of Magnesium chloride which could result in a higher serum level.

IMPORTANT PRESCRIBING INFORMATION Temporary …

Cefotaxime sodium for Injection, BP in the dry state should be stored at room temperature (15-25°C), protected from light and heat. The dry powder as well as solutions tend to darken, depending ...

Solubility of Cefotaxime Sodium in Ethanol + Water ...

Solubility of Cefotaxime Sodium in Ethanol + Water Mixtures under Acetic Acid Conditions Article in Journal of Chemical & Engineering Data 59(6):1865–1871 · May 2014 with 206 Reads

Cefotaxime 2g Powder for Solution for Injection or ...

May 28, 2020· For long lasting intravenous infusion 2 g Cefotaxime should be dissolved in 100 ml of Water for Injections or another suitable fluid, e.g. 0.9% sodium chloride or isotonic glucose solution or other compatible fluids for infusions. After preparation, the solution may be given as a 50-60 minute intravenous infusion.

CEFOTAXIME SODIUM FOR INJECTION 500MG 1G | Drugs.com

Cefotaxime (as Cefotaxime sodium) per vial 500mg 1g Diluent to be added Final concentration of solution 2ml 4ml 500mg/ 2.2ml 1g/ 4.4ml Intravenous Injection Cefotaxime Sodium for Injection 500mg is dissolved in at least 2 ml water for injections, Cefotaxime Sodium for Injection 1 g in at least 4 ml

Chemistry of cefotaxime | Journal of Antimicrobial ...

This problem has been solved by building the aminothiazole ring on to an existing syn-methoxy-imino acetic acid derivative and condensing the resulting pure syn-methoxy-iminoaminothiazole acetic acid with 7-amino cephalosporanic acid. The stable crystalline sodium salt, cefotaxime, is readily obtained by adding the free acid to an aqueous ...

SYNTHESIS OF CEFOTAXIME FROM DAMA (DIETHYL …

INTRODUCTION: Cefotaxime Sodium is sodium 7-[2-(2-amino-4-thiazolyl) glyoxylamido]-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo [4.2.0] oct-2-ene-2-carboxylate 72 (Z)-(o-methyloxime), acetate (ester) with molecular formula C 16 H 16 N 5 NaO 7 S 2 1.Cefotaxime is a third-generation parenteral cephalosporin antibacterial used in the treatment of infections due to susceptible Gram …

Cefotaxime - Wikipedia

Cefotaxime is an antibiotic used to treat a number of bacterial infections. Specifically it is used to treat joint infections, pelvic inflammatory disease, meningitis, pneumonia, urinary tract infections, sepsis, gonorrhea, and cellulitis. It is given either by injection into a vein or muscle.

cefotaxime sodium (CHEBI:3498)

cefotaxime sodium: ChEBI ID CHEBI:3498: Definition A cephalosporin organic sodium salt having acetoxymethyl and [2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side-groups. Stars This entity has been manually annotated by the ChEBI Team.

Cefotaxime sodium - wikidoc

If C. trachomatis is a suspected pathogen, appropriate anti-chlamydial coverage should be added, because cefotaxime sodium has no activity against this organism.. To prevent postoperative infection in contaminated or potentially contaminated surgery, the recommended dose is a single 1 gram IM or IV administered 30 to 90 minutes prior to start of surgery.

DailyMed - CEFOTAXIME injection

Oct 15, 2018· Sterile Cefotaxime for Injection, USP, in Pharmacy Bulk Packages, is a dry off-white to pale yellow crystalline powder containing cefotaxime sodium as follows: 10 g cefotaxime (free acid equivalent) in bottles, packages of 1 (NDC 0143-9935-01); …

ABOUT US-Cefotaxime Sodium,Cefotaxime Acid,Ceftriaxone ...

The main product is sterile cefotaxime sodium and cefotaxime acid. As a result of advanced and eco-friendly production technology, the product is in the leading level not only in the domestic industry but also exported to international market such as Europe, United States, Russia, southeast Asia, Africa and other countries and regions.

Cefotaxime 500mg/1g Powder for solution for injection or ...

Jun 15, 2017· Compound Sodium Lactate Intravenous Infusion BP (Ringer-lactate solution for injection) Intravenous Infusion: 1-2g cefotaxime are dissolved in 40-100ml of infusion fluid. After 24 hours any unused solution should be discarded. Cefotaxime is compatible with 1% Lidocaine Injection BP; however freshly prepared solutions should be used.

CEFODIZIME SODIUM PDF

Floctafenine The risk or severity of nephrotoxicity can be increased when Cefotaxime is combined with Floctafenine. Phosphoric acid Cefotaxime may decrease the excretion rate of Phosphoric acid which could result in a higher serum level. Pegaptanib Cefotaxime may decrease the excretion rate of Pegaptanib which could result in a higher serum level.

Drugs Details » Cefotaxime : Drug class, mechanism of ...

Cefotaxime sodium contains approximately 51 mg (2.2 mEq) per each gram in parenteral form. The frozen solutions of cefotaxime sodium are additionally formulated with sodium hydrate as a buffer. In patients with conditions that may require sodium restriction (such as congestive heart failure, hypertension, and fluid retention), the sodium ...

USP Monographs: Cefotaxime Sodium

in which C is the concentration, in mg per mL, of USP Cefotaxime Sodium RS in the Standard preparation; P is the designated content, in µg per mg, of cefotaxime (C 16 H 17 N 5 O 7 S 2) in USP Cefotaxime Sodium RS; W is the weight, in mg, of Cefotaxime Sodium taken to prepare the Assay preparation; and r U and r S are the cefotaxime peak area ...

Cefotaxime - Wikipedia

Synonym: Cefotaxime, Sodium Salt, High Purity, Cell Culture-Tested - CAS 64485-93-4 - Calbiochem Empirical Formula (Hill Notation): C 16 H 16 N 5 NaO 7 S 2 Molecular Weight: 477.45

Cefotaxime 1g powder for solution for injection vials ...

Cefotaxime sodium may be administered intravenously, by bolus injection or infusion, or intramuscularly. The dosage, route and frequency of administration should be determined by the severity of infection, the sensitivity of causative organisms and condition of the patient. Therapy may be initiated before the results of sensitivity tests are known.

Cefotaxime sodium | C16H16N5NaO7S2 - PubChem

Cefotaxime Sodium is the sodium salt form of cefotaxime, a beta-lactam, third-generation cephalosporin antibiotic with bactericidal activity.Cefotaxime sodium binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall.Inactivation of PBPs interferes with the cross-linking of peptidoglycan chains necessary for bacterial cell wall strength ...

APExBIO - Cefotaxime (sodium salt) | cephalosporin ...

MIC: . 0.1 μg/ml for S. pneumoniae Cefotaxime is a cephalosporin antibiotic. The cephalosporins, a class of β-lactam antibiotics originally derived from the fungus Acremonium, are indicated for the prophylaxis and treatment of infections caused by bacteria susceptible to this particular form of antibiotic.

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